Characterization of cancer stem cell in glioblastoma, sarcoma, and various metastatic cancers
Precision medicine: development of personalized anti-cancer treatment based on genomic characteristics of cancers
Clinical utilzations of neural stem cells expressing therapeutic genes
학력
(Ph.D.) Seoul National University College of Medicine 2006
(M.D.) Seoul National University College of Medicine 2002
약력/경력
Professor, SungKyunKwan University School of Medicine (2018-Present)
Visiting Research Scholar, Duke University Medical Center (2014-2015)
Associate professor, SungKyunKwan University School of Medicine (2013-2018)
Assistant professor, SungKyunKwan University School of Medicine (2012-2013)
Assistant professor, Seoul National University College of Medicine (2009-2012)
Public Health Doctor, National Forensic Service (2006-2009)
학술지 논문
(2023)
Effects of ethanol washing and storage duration on primary culture of stem cells from human exfoliated deciduous teeth.
Journal of Oral Biology and Craniofacial Research.
13,
5
(2023)
Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.
NEOPLASIA.
39,
(2023)
Application of RapidHIT™ ID for cell authentication by fast and convenient STR profiling.
GENES & GENOMICS.
45,
10
(2022)
Advances in Neural Stem Cell Therapy for Spinal Cord Injury: Safety, Efficacy, and Future Perspectives.
NEUROSPINE.
19,
4
(2022)
JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models.
AGING-US.
14,
22
(2022)
Functional validation of the simplified in vitro 3D Co-culture based BBB model.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
625,
(2022)
Simplified in vitro 3D co-culture-based blood-brain barrier model using transwell.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
620,
(2022)
Combination stem cell therapy using dental pulp stem cells and human umbilical vein endothelial cells for critical hindlimb ischemia br.
BMB REPORTS.
55,
7
(2022)
Significant Therapeutic Effects of Adult Human Neural Stem Cells for Spinal Cord Injury Are Mediated by Monocyte Chemoattractant Protein-1 (MCP-1).
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
23,
8
(2022)
Thrombin Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in Severe Intraventricular Hemorrhage Induced Neonatal Rats.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
23,
8
(2022)
Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells.
STEM CELL REVIEWS AND REPORTS.
18,
1
(2022)
The effects of early exercise in traumatic brain-injured rats with changes in motor ability, brain tissue, and biomarkers.
BMB REPORTS.
55,
10
(2021)
합성수지 점토를 이용한 심장발생 모델링 실습 방법 제안.
해부·생물인류학.
34,
4
(2021)
Adult Human Multipotent Neural Cells Could Be Distinguished from Other Cell Types by Proangiogenic Paracrine Effects via MCP-1 and GRO.
STEM CELLS INTERNATIONAL.
2021,
(2021)
Challenging Microvascular Decompression Surgery for Hemifacial Spasm.
WORLD NEUROSURGERY.
151,
(2021)
Optimal preclinical conditions for using adult human multipotent neural cells in the treatment of spinal cord injury.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
22,
5
(2020)
Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient.
GENOME MEDICINE.
12,
1
(2019)
Elucidation of Novel Therapeutic Targets for Acute Myeloid Leukemias with RUNX1-RUNX1T1 Fusion.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
20,
7
(2019)
Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain.
GEROSCIENCE.
41,
2
(2018)
Optimized Clump Culture Methods for Adult Human Multipotent Neural Cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
19,
11
단행본
(2018)
Gene Therapy in Neurological Disorders.
Academic Press.
공동
수상/공훈
2012 Scientist of the year, Korean Association of Anatomist
2009 Hoshino award in the 3rd quadrennial meeting of the world federation of neuro-oncology jointly with the 6th meeting of the asian society for neuro-oncology (ASNO)
2008 Travel award in the 6th ISSCR annual meeting of the International society for stem cell research
학술회의논문
(2012)
Development of therapeutic methods for neurodegenerative diseases using neural stem cells expressing indolamine 2,3-dioxygenase(IDO).
제62회 대한해부학회 학술대회.
대한민국
(2012)
Gene silencing of c-Met leads to brain metastasis inhibitory effects.
제62회 대한해부학회 학술대회.
대한민국
(2012)
Met signaling regulates glioblastoma stem cells.
제62회 대한해부학회 학술대회.
대한민국
